Testosterone Injections: In general, dosages will vary between 50 mg and 300 mg per injection, depending on the ester and the dosing regimen. An average injectable dose is about 200-250 mg every two weeks, though many trans men inject 100 mg every week or every 10 days, or other variations depending on their own bodies’ needs and sensitivities. Again, the exact dosage required will vary from person to person, and health and well-being should be carefully monitored while determining an individual’s ideal dose. Here are some types of injectable esters used for testosterone therapy:
Testosterone enanthate: Chemical formula C26H40O3
Testosterone enanthate is one of the main forms of testosterone prescribed to men in the United States. It is a slow-acting ester with a release time between 8-10 days. The name-brand of T-enanthate available in the United States is called “Delatestryl,” which is suspended in sesame oil. Testosterone enanthate is typically injected anywhere between once every week to once every three weeks. Generic testosterone enanthate can also be obtained through a compounding pharmacy; such pharmacies can mix the enanthate in either sesame or cotton seed oil.
Testosterone cypionate: Chemical formula C27H40O3
Testosterone cypionate is the other main injectable form of testosterone prescribed to men in the United States. It is a slow-acting ester with a release time between 8-10 days, similar to that of enanthate. The name-brand of T-cypionate available in the United States is called “Depo-Testosterone,” which is suspended in cottonseed oil. Testosterone cypionate is typically injected anywhere between once every week to once every three weeks. Generic testosterone cypionate can also be obtained through a compounding pharmacy; such pharmacies can mix the cypionate in either sesame or cotton seed oil.
Sustanon 100 or 250:
“Sustanon” is the brand name for two formulas of injectable testosterone that contain a blend of esters. “Sustanon 100″ contains three testosterone esters: testosterone propionate (C22H32O3), testosterone phenylpropionate (C28H36O3), and testosterone isocaproate (C25H3803). “Sustanon 250″ contains four testosterone esters: testosterone propionate (C22H32O3), testosterone phenylpropionate (C28H36O3), testosterone isocaproate (C25H3803), and testosterone decanoate (C29H4603). Both formulas feature both fast-acting and slow-acting esters, and can be injected anywhere from once every week to once every four weeks. Sustanon is prescribed outside of the United States.
Testosterone Creams & Gels: Most doctors that prescribe testosterone will provide it in cream or gel form because the pharmaceutical companies are marketing these products, such as Androgel and Testim, a great deal. The down fall to the creams or gels is that it can be transferred to other people like partners and children, when in close contact, but it can be avoided if it is kept covered. Also, absorption rates vary from very good, to extremely poor, but once absorbed through the skin, the gels and creams are very fast-acting. Thus, it must be applied once or twice daily to maintain T levels. This transdermal method is popular with those that do not like needles or injections.
Testosterone Pills: Testosterone pills, like Andriol, are another new testosterone formulation. They have horrendous absorption rates, need to be taken with large amounts of fats, and are quite expensive. They are not effective because they are absorbed and deactivated by the liver too quickly. You will most likely only get to the mid range of normal for your blood tests; hardly good for a successful therapy.
Testosterone Patches & Subcutaneous Testosterone Pellets: The testosterone pellets are pure crystalline testosterone implanted under the skin. They are about the size of a grain of rice, and are typically placed in the buttocks or abdomen. The insertion of the pellets is a quick procedure, usually done under local anesthesia. Pellets are typically replaced after 3-4 months. “Testopel” is a brand name for testosterone pellets in the United States. A 200 mg testosterone pellet releases testosterone at a steady rate of 1-3 mg per day. Several pellets can be inserted at the same time to increase dosage.
The patches, like Testoderm and Androderm, are placed on the skin. There two forms of Testoderm available: a non-scrotal patch (Testoderm TTS) and a scrotal patch. Both Androderm and Testoderm TTS are very fast-acting once they have permeated the skin. The testosterone in the patches is suspended in an alcohol-based gel. In order to deliver the testosterone efficiently into the body, chemical enhancers are added to the patch to increase permeability of the skin. It is these enhancers that are often the cause of skin irritation in many users. Some individuals find Testoderm TTS to be less irritating to the skin than Androderm, but this will vary from person to person.
The pellets and patches are not used very widely anymore due to their low absorbtion rates and difficulty of use. The patch does not stay on well enough and causes rashes on some people and the pellets are just hard to use and sometimes work their way out from under the skin.